When an element is set to Focusable="True", it should receive keyboard and gamepad navigation - like in WPF.

The code below allows in WPF to navigate out of the list into the two textblock that are focusable.

<StackPanel KeyboardNavigation.DirectionalNavigation="Contained">
    <StackPanel.Resources>
        <Style x:Key="FocusableText" TargetType="TextBlock">
            <Setter Property="Focusable" Value="True" />
            <Style.Triggers>
                <Trigger Property="IsKeyboardFocused" Value="True">
                    <Setter Property="Foreground" Value="Red" />
                </Trigger>
            </Style.Triggers>
        </Style>
    </StackPanel.Resources>

    <TextBlock Text="Element 1" Style="{StaticResource FocusableText}" />
    <TextBlock Text="Element 2" Style="{StaticResource FocusableText}" />
    <ListBox x:Name="MyList" KeyboardNavigation.DirectionalNavigation="Continue">
        <ListBoxItem>
            <TextBlock Text="List 1" />
        </ListBoxItem>
        <ListBoxItem>
            <TextBlock Text="List 2" />
        </ListBoxItem>
        <ListBoxItem>
            <TextBlock Text="List 3" />
        </ListBoxItem>
    </ListBox>
    <b:Interaction.Triggers>
        <b:EventTrigger EventName="Loaded">
            <noesis:SetFocusAction TargetName="MyList"/>
        </b:EventTrigger>
    </b:Interaction.Triggers>
</StackPanel>